Background: Cutaneous mesothelioma is rare but may occur following local surgical procedures for visceral mesothelioma or as a metastasis.Methods: A patient with pleural mesothelioma, who developed papules within chest wall scars, 14 and 15 months after pleural biopsy and thoracentesis, respectively, is reported.Results: Histopathology showed an epithelioid tumor forming tubulopapillary and glandular structures.The diagnosis of mesothelioma was confirmed with immunohistochemistry.Tum…
To evaluate medical thoracoscopy in the diagnosis and treatment of pleural mesothelioma. Twenty-one patients with pleural mesothelioma were studied, 17 male and 4 female, with a mean age of (62±12) years. All were brought into medical thoracoscopy after three consecutive pleurorrhea cytology and percutaneous pleural biopsy. The patients with diffuse pleural mesotheloima underwent pleurodesis after thoracoscopy. The diagnostic yield of all three techniques compared, complications and the effect …
Objective To investigate differential diagnosis of mesothelioma by means of the combined examinations of sections and smears of the deposits of pleural and peritoneal effisions.Methods Successive sections and smears of the deposits of 52 cases of mesothelioma were studied,in which 46 cases were testified by histology and 6 cases had typical clinical characteristics.Results All of 52 cases of mesothelioma were detected by means of section method,while only 38 cases were detected by means of smear method,its …
Objective To study the presence of simian virus-40(SV40)DNA in tissue sections of malignant mesothelioma and to evaluate the relation of prognosis. Methods We reviewed 60 cases of malignant mesothelioma confirmed by the methods of histology,immunohistochemistry and electron microscopy.The polymerase chain reaction was applied to detect the presence of SV40 DNA in tissue sections of malignant mesothelioma.Results SV40 DNA was detected in the tissue of malignant mesothelioma(60%).We al…
Malignant pleural mesothelioma(MPM),originated from pleural mesothelium cell,is a fatal tumor with atypical manifestation and poor clinical outcome.Here we present a review of the manifestations of MPM by several imaging methods(X-ray,CT,MRI and PET/CT),with a discussion in the values of thoses methods in the diagnosis,staging and prognosis of pleural mesothelioma.
To study the pathological diagnosis,differential diagnosis and prognosis of lymphohistiocytoid mesothelioma(LHM).Methods Histopathological characteristics and immunohistochemical findings were studied in two cases of LHM with review of the literatures.Results Paients presented with chest pain in two cases.The tumors showed a diffuse proliferation of large,atypical fibrohistiocytoid cells intermixed with numerous lymphocytes,plasma cells and occasional eosinophils.Ultrastructurally,the cases …
To investigate the diagnosis and treatment of malignant pleural mesothelioma(MPM).Methods The clinical data of 18 cases with MPM covering a period frome 1999 to 2006 were analyzed retrospectively.Results Of all the 18 cases,11 cases are male,7 cases are female,male:female=1.6:1,patients age.The main symptoms were chest pain(15/18),dyspnea(12/18),cough(9/18);Through the radiologic findings,we could find 15 cases showing plenty of pleural effusion and with pleural thickening among 10 of them;I…
Objective Malignant mesothelioma is a mesothelium-derived carcinoma with high malignancy.Insulin-like growth factor and other growth factors were reported to be associated with the pathogenesis and prognosis of malignant mesothelioma.And some of these growth factors might be new targets of chemotherapy.
To assess the diagnosis of thoracoscopy in pleural mesothelioma. Methods Thoracoscopy with a single opening was performed using a rigid thoracoscopy under general anesthesia with neuroleptunalgesia.Biopsies were taken under visual control for optical microscopic examination. Result All of 8cases had underwent and toleranced the thoracoscopy.The biopsies were taken smoothly. General pathologic examenation the pleural mesothelioma. Conclusion Thoracoscopy is a safe and effective measure …
Masothelioma,a rare tumor,usually occurred in pleura,peritoneum and cardiac pericardium and so on.The majority is malignant,with short surviving period and high mortality.Malignant pleural mesothelioma is related with asbestos exposure,but the other causes are still unclear.This paper summarizes its epidemiology distribution,hazardous factors,the measures of control and prevention presently and so on.